Pesquisa sobre:
PRE-B CELL RECEPTORS
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DeCS
Descritor
Inglês
:
Pre-B Cell Receptors
Descritor
Espanhol
:
Receptores de Células Precursoras de Linfocitos B
Descritor
Português
:
Receptores de Células Precursoras de Linfócitos B
Sinônimos
Inglês
:
Pre-B Cell Receptor
Cell Receptor, Pre-B
Cell Receptors, Pre-B
Pre B Cell Receptor
Pre B Cell Receptors
Receptor, Pre-B Cell
Receptors, Pre-B Cell
Categoria:
D12.776.124.486.485.950.750
D12.776.124.790.651.950.750
D12.776.377.715.548.950.750
D12.776.543.750.705.816.821.750
Definição
Inglês
:
Membrane proteins
in precursor
B-LYMPHOCYTES
(pre-B Cells). They are composed of membrane-bound MU
IMMUNOGLOBULIN HEAVY CHAINS
in complex with SURROGATE LIGHT CHAINS instead of conventional
IMMUNOGLOBULIN LIGHT CHAINS
. Only successful rearrangement of the VDJ segments, at the Ig heavy chain gene locus (IMMUNOGLOBULIN HEAVY CHAIN GENES), will generate mu heavy chains that can pair with surrogate light chains. Thus formation of the
pre-B cell receptors
is an important checkpoint in the development of mature B cells.
Nota Histórica
Inglês
:
2008
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Número do Registro:
52788
Identificador Único:
D054420
Ocorrência na BVS
:
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